2012

Mazzaglia, A, DJ Studholme, MC Taratufolo, R Cai, NF Almeida, T Goodman, DS Guttman, BA Vinatzer, GM Balestra, 2012. Pseudomonas syringae pv. actinidiae (PSA) isolates from recent bacterial canker of kiwifruit outbreaks belong to the same genetic lineage. PLoS One, in press.

McCann, HC, H Nahal, S Thakur & DS Guttman, 2012.  Identification of novel innate immunity elicitors using molecular signatures of natural selection.  Proceedings of the National Academy of Sciences, USA,  vol. 109 no. 11 4215-4220. [pdf]
- Commentary: by Brunner, F & T Nürnberger, 2012. Identification of immunogenic microbial patterns takes the fast lane PNAS 2012 109 (11) 4029-4030.

Lewis, JD, J Wan, R Ford, Y Gong, P Fung, H Nahal, PW Wang, D Desveaux† & DS Guttman†, 2012.  Quantitative interactor screening with next-generation sequencing (QIS-Seq) identifies Arabidopsis thaliana MLO2 as a target of the Pseudomonas syringae type III effector HopZ2.  BMC Genomics. 13(1): 8. [pdf]

Lee, AHY, B Hurley, C Felsensteiner, C Yea, W Ckurshumova, V Bartetzko, PW Wang, V Quach, JD Lewis, YC Liu, F Börnke, S Angers, A Wilde, DS Guttman† & D Desveaux†, 2012.   A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion.  PLoS Pathogens, 8(2): e1002523. [pdf]

Lee, S-J, J Lee, KK Li, D Holland, H Maughan, DS Guttman, B Yusta & DJ Drucker,  2012. Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis. Endocrinology,  153(3):1141-1151.

Stavrinides J, MWB Kirzinger, F Beasley & DS Guttman, 2012.  E622: a bacterial virulence-associated miniature inverted-repeat transposable element.  Journal of Bacteriology, 194(2):509-517. [pdf]

Maughan H, KS Cunningham, PW Wang, Y Zhang, M Cypel, C Chaparro, DE Tullis, TK Waddell, S Keshavjee, M Liu, DS Guttman & DM Hwang, 2012.  Pulmonary bacterial communities in surgically resected non-cystic fibrosis bronchiectasis lungs are similar to those in cystic fibrosis. Pulmonary Medicine. 746358. [pdf]

Sohn KH, SB Saucet, CR Clarke, BA Vinatzer, HE O’Brien, DS Guttman & JDG Jones, 2012.  HopAS1 recognition significantly contributes to Arabidopsis nonhost resistance to Pseudomonas syringae pathogens.  New Phytologist 193(1):58-66. [pdf]

O’Brien HE, Y Gong, P Fung, PW Wang & DS Guttman, 2011.  Use of low-coverage, large-insert, short-read data for rapid and accurate generation of enhanced-quality draft Pseudomonas genome sequences. PLoS One. 6(11) e27199 [pdf]

Nasmith GC, S Walkowiak, L Wang, WWY Leung, Y Gong, A Johnston, L Harris, DS Guttman & R Subramaniam,  2011.  Tri6 is defined as a broad domain transcription regulator in the phytopathogen Fusarium graminearum  PLoS Pathogens 7(9): e1002266 [pdf]

Austin RS, D Vidaurre, G Stamatiou, R Breit, NJ Provart, D Bonetta, J Zhang, P Fung, Y Gong, PW Wang, P McCourt & DS Guttman,  2011.  Next-generation mapping of Arabidopsis genes.  The Plant Journal 67(4): 715-725.  [pdf]

O'Brien HE, S Thakur & DS Guttman 2011. Evolution of Plant Pathogenesis in Pseudomonas syringae: A genomic perspective. Annual Review of Phytopathology 49:17.1–17.21 [pdf]

Lewis JD, A Lee, W Ma, H Zhou, DS Guttman† & D Desveaux†,  2011.  The YopJ superfamily in plant-associated bacteria.  Molecular Plant Pathology 12(9): 928-937. [pdf]

MacDonald J, M Doering, T Canam, Y Gong, DS Guttman, M Campbell & E Master,  2011. Transcriptomic responses of the softwood-degrading white-rot fungus Phanerochaete carnosa during growth on coniferous and deciduous wood. Applied & Environmental Microbiology.  77(10):3211-3218. [pdf]

O'Brien HE, D Desveaux, & DS Guttman,  2011.  Next-generation genomics of Pseudomonas syringae. Current Opinion in Microbiology 14(1):24-30. [pdf]

Anderson JB, J Funt, DA Thompson, S Prabhu, A Socha, C Sirjusingh, JR Dettman, L Parreiras, DS Guttman, A Regev & LM Kohn,  2010.  Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populations. Current Biology 20(15): 1383-1388. [pdf]

Lewis, JD, R Wu, DS Guttman† & D Desveaux†,  2010.  Allele-specific virulence attenuation of the Pseudomonas syringae HopZ1a type III effector via tha Arabidopsis ZAR1 resistance protein. PLoS Genetics 6(4): e1000894. [pdf]

Almeida, NF, S Yan, R Cai, CR Clarke, CE Morris, NW Schaad, EL Schuenzel, GH Lacy, X Sun, JB Jones, JA Castillo, CT Bull, S Leman, DS Guttman JC Setubal & BA Vinatzer, 2010. PAMDB, a multilocus sequence typing and analysis database and website for plant-associated microbes. Phytopathology 100(3):208-215. [pdf]

Clark, CR, R Cai, DJ Studholme, DS Guttman & BA Vinatzer, 2010.  Pseudomonas syringae strains naturally lacking the classical P. syringae hrp/hrc locus are common leaf colonizers equipped with an atypical type III secretion system.  Molecular Plant-Microbe Interactions.  23(2): 198-210. [pdf]

Guttman, DS, 2009  Bacterial Evolution: dynamic genomes and the power of transformation. Current Biology. 19(18): R857-R859. [pdf]

Lewis, JD, DS Guttman† & D Desveaux†, 2009  The targeting of plant cellular systems by injected type III effectors. Seminars in Cell & Developmental Biology. 20(9):1055-63 [pdf]

Pitout, JDD, L Campbell, DL Church, DS Guttman & DB Gregson,  2009. Using a commercial semi-automated repetitive sequence-based PCR typing technique for the identification of Escherichia coli clone ST131 producing CTX-M-15.  Journal of Clinical Microbiology. 4: 1212-1215. [pdf]

Zhou J, RL Morgan, DS Guttman & W Ma.  2009.  Allelic variants of the Pseudomonas syringae type III effector HopZ1 are differentially recognized by plant resistance systems.  Molecular Plant-Microbe Interactions. 22(2): 176-189 [pdf]

Singh S, J Stavrinides, D Christendat† & DS Guttman†, 2008.  A phylogenomic analysis of the shikimate dehydrogenases reveals broadscale functional diversification and identifies one functionally distinct subclass. Molecular Biology & Evolution. 25: 2221-2232. [pdf]

Ma, W & DS Guttman  2008.  Evolution of prokaryotic and eukaryotic virulence effectors. Current Opinion in Plant Biology.  11:412-419. [pdf]

Tan J, DD Pitout & DS Guttman.  2008. Rapid and sensitive assessment of Pseudomonas aeruginosa metallo beta-lactamase resistance to imipenem.  Journal of Clinical Microbiology. 46: 1870-1872. [pdf]

Lewis, JD, W Abada, W Ma, DS Guttman† & D Desveaux†, 2008. The HopZ family of Pseudomonas syringae type III effectors require myristoylation for virulence and avirulence functions in Arabidopsis. Journal of Bacteriology, 190:2880-2891. [pdf]

Stavrinides, J, HC McCAnn & DS Guttman, 2008. Host-pathogen interplay and the evolution of bacterial effectors.  Cellular Microbiology 10(2):285-92. [pdf]

McCann, HC & DS Guttman, 2008. The evolution of the type III secretion system in plant-microbe interactions.  New Phytologist 177(1):33-47. [pdf]

Wang, PW, M Scortichini, RL Morgan & DS Guttman,  2007.  Convergent evolution of phytopathogenic Pseudomonads to a common host.  Microbiology 153: 2067-2073. [pdf]

Ma, W, F Dong, J Stavrinides & DS Guttman, 2006. Type III effector diversification via both pathoadaptation and horizontal transfer in response to a coevolutionary arms race. PLoS Genetics, 2(12): e209. [pdf]

Stavrinides, J, W Ma & DS Guttman, 2006. Terminal reassortment drives the quantum evolution of type III effectors in bacterial pathogens. PLoS Pathogens 2(10): e104. [pdf]

Guttman, DS, SJ Gropp, RL Morgan & PW Wang, 2006. Diversifying Selection Drives the Evolution of the Type III Secretion System Pilus of Pseudomonas syringae. Molecular Biology and Evolution. 23(12): 2342-2354. [pdf]

Sarkar, SF, JS Gordon, GB Martin & DS Guttman, 2006. The comparative genomics of host-specific virulence in Pseudomonas syringae. Genetics, 174: 1041-1056. [pdf]

Vencato, M, F Tian, JR Alfano, CR Buell, S Cartinhour, GA DeClerck, DS Guttman, J Stavrinides, V Joardar, M Lindeberg, PA Bronstein, JW Mansfield, CR Myers, A Collmer & DJ Schneider, 2006. Bioinformatics-enabled inventory of the Hrp regulon and type III secretion system effector proteins of Pseudomonas syringae pv. phaseolicola 1448A. Molecular Plant-Microbe Interactions. 19(11): 1193-1206. [pdf]

Hwang, MSH., RL Morgan, SF Sarkar, PW Wang & DS Guttman, 2005. Phylogenetic characterization of virulence and resistance phenotypes in Pseudomonas syringae. Applied and Environmental Microbiology 71(9): 5182-5191. [pdf]

Lindeberg, M, J Stavrinides, JH Chang, JR Alfano, A Collmer, JL Dangl, JT Greenberg, JW Mansfield & DS Guttman, 2005. Unified nomenclature and phylogenetic analysis of extracellular proteins delivered by the type III secretion system of the plant pathogenic bacterium Pseudomonas syringae. Molecular Plant-Microbe Interactions 18(5): 275-282. [pdf]

Stavrinides J & DS Guttman, 2004. Nucleotide sequence and evolution of the five-plasmid complement of the phytopathogen Pseudomonas syringae pv. maculicola ES4326. Journal of Bacteriology 186(15): 5101-5115. [pdf]

Sarkar SF & DS Guttman. 2004. The evolution of the core genome of Pseudomonas syringae, a highly clonal, endemic plant pathogen. Applied and Environmental Microbiology 70(4): 1999-2012. [pdf]

Gropp SJ & DS Guttman, 2004. The PCR amplification and characterization of entire Pseudomonas syringae hrp/hrc clusters. Molecular Plant Pathology 5(2): 137-140 [pdf]

Rohmer L, DS Guttman & JL Dangl, 2004. Diverse evolutionary mechanisms shape the type III effector virulence factor repertoire in plant pathogenic Pseudomonas syringae. Genetics 167: 1341-1360 [pdf]

Guttman DS, 2004. Plants as models for the study of human pathogenesis. Biotechnology Advances 22: 363-382. [pdf]

Guttman DS & SF Sarkar, 2004. Evolutionary and functional genomics of host specificity in Pseudomonas syringae. in Biology of Molecular Plant-Microbe Interactions. vol 4, B. Lugtenberg, I. Tikhonovich and N. Provorov eds. Internation Society for Molecular Plant-Microbe Interactions publisher. pp132-137.

Wang PW, L Chu & DS Guttman, 2004. Complete sequence and evolutionary genomic analysis of the Pseudomonas aeruginosa transposable bacteriophage D3112. Journal of Bacteriology 186(2): 400-410 [pdf]

Stavrinides J & DS Guttman, 2004. Mosaic evolution of the Severe Acute Respiratory Syndrome coronavirus. Journal of Virology 78(1): 76-82 [pdf] [supp data]

Guttman DS, B Vinatzer, SF Sarkar, MV Ranall, G Kettler & JT Greenberg, 2002. A functional screen for the type III (Hrp) secretome of the plant pathogen Pseudomonas syringae. Science 295: 1722-1726. [pdf]

Guttman DS & JT Greenberg, 2000. Functional analysis of type III effectors of Pseudomonas syringae using a single copy genomic integration system. Molecular Plant-Microbe Interactions 14(2): 145-155. [pdf]

Rate DN, JV Cuenca, GR Bowman, DS Guttman & JT Greenberg, 1999. A gain-of-function Arabidopsis acd6 mutant reveals novel regulation and function of the salicylic acid signaling pathway in controlling cell death, defenses and cell growth. Plant Cell 11: 1695-1708. [pdf]

Charlesworth D & DS Guttman, 1999. The evolution of dioecy and plant sex chromosome systems. In Sex Determination in Plants, C.C. Ainsworth editor, BIOS Scientific Publishers Limited, Oxford, pp 25-49.

Guttman DS & D Charlesworth, 1998. An X-linked gene with a degenerate Y-linked homologue in a dioecious plant. Nature 393: 263-266. [pdf]

Guttman DS, 1997. Recombination and clonality in natural populations of Escherichia coli. Trends in Ecology and Evolution 12: 16-22. [pdf]

Charlesworth B, D Charlesworth, J Hnilicka, A Yu  DS Guttman, 1997. Lack of degeneration of loci on the neo-Y chromosome of Drosophila americana. Genetics 145: 989-1002.

Charlesworth D  DS Guttman, 1997. Plant Genetics: Seeing selection in S allele sequences. Current Biology 7: R34-R37.

Charlesworth B  DS Guttman, 1996. Reductions in genetic variation in Drosophila and E. coli caused by selection at linked sites. Journal of Genetics 75: 49-61.

Guttman DS, PW Wang, I-N Wang, EM Bosler, BJ Luft & DE Dykhuizen, 1996. Multiple infection of Ixodies scapularis ticks by Borrelia burgdorferi as revealed by single-strand conformation polymorphism analysis. Journal of Clinical Microbiology 34: 652-656. [pdf]

McGrath BC, JJ Dunn, G Gorgone, BJ Luft, DS Guttman  DE Dykhuizen, 1995. Identification of an immunologically important hypervariable domain of major outer surface protein A of Borrelia burgdorferi. Infection and Immunity 63: 1556-1361.

Guttman DS  DE Dykhuizen, 1994. Clonal divergence in Escherichia coli as a result of recombination, not mutation. Science 266: 1380-1383. [pdf]

Guttman DS  DE Dykhuizen, 1994. Detecting selective sweeps in naturally occurring microorganisms. Genetics 138: 993-1003. [pdf]